SSRIs & Depression: No Longer a Social Stigma

There is often a social stigma associated withbecause they seem to affect only serotonin, not
clinical depression, that a person who suffers fromother neurotransmitters.
depression has a certain negative personality or isAntidepressants  may also play a
a loner, etc.  But this stigma is quite far from theneuroprotective role in how they relieve anxiety
biological truth.  By understanding the biologicaland depression by increasing the effects of brain
mechanism of depression and the role ofreceptors that help nerve cells keep sensitivity to
serotonin and the medications used to treat it,glutamate — an organic compound of a
SSRIs, (selective serotonin reuptake inhibitors) cannonessential amino acid — in check. This
help to dismantle this notion.  You see, there areincreased support of nerve cells lowers sensitivity
brain chemicals called neurotransmitters associatedto glutamate and provides protection against the
with depression, including the neurotransmitterglutamate overwhelming and exciting key brain
serotonin and some research suggests thatareas related to anxiety and depression.
abnormalities in neurotransmitter activity affectAntidepressant medications are often the first
mood and behavior as in depression.  Whattreatment choice for adults with moderate or
SSRIs do is relieve symptoms of depression bysevere depression, sometimes along with
blocking the reabsorption (reuptake) of serotoninpsychotherapy. Although antidepressants may not
by certain nerve cells in the brain, leaving morecure depression, they can help you achieve
serotonin around in the brain. This enhancesremission — the disappearance or nearly
neurotransmission, the sending of nerve impulsescomplete reduction of depression symptoms.
and improves mood. SSRIs are called selective