Sudden Cardiac Arrest - Is There Hope?

On June 25, 2009, Michael Jackson, well-known as(7) Unknown causes. Unfortunately, a lot of cases
the King of Pop, died of cardiac arrest.of SCA are put down to unknown causes, often
Cardiovascular disease (CVD) is the leading causein young, healthy people with no apparent heart
of mortality in the U.S. and the majority of CVDdisease or other risk factors.
deaths are attributable to Sudden Cardiac ArrestHow can death from SCA be prevented? Not
(SCA) which claims more than 250,000 lives eacheasy, in fact, 95% of SCA cases are fatal. To
year. One person dies of SCA-related eventshave a chance of surviving, victims of SCA must
every two minutes. This is equivalent to morereceive life-saving defibrillation within the first 4 to
650 deaths each day. Each year, more people die6 minutes of an attack, when brain and organ
from SCA than from breast cancer, lung cancer,damage start to occur.
stroke, or AIDS combined. 95% of SCA casesFollowing are ways to restart the heart during
are fatal and two-thirds of SCA events occur inSCA:
people without any previous indications of heart(1) Defibrillators. These are the so-called paddles
disease.applied to the chest to deliver an electric shock to
According to the American Heart Associationmake the heart beat again. Defibrillators are only
(AHA), SCA occurs when electrical impulses in theavailable in emergency services and hospitals and
heart become rapid or chaotic, which causes thecan only be operated by medical professionals.
heart to suddenly stop beating. The blood supply(2) Automatic External Defibrillators (AEDs) are
to the rest of the body ceases and without thebattery-operated portable defibrillators. Current
blood supply, the oxygen supply is also cut off,AEDs are designed to be operable by almost
resulting in tissue damage and death. Because ofanybody, even without formal medical training.
its suddenness, cardiac arrest is also called suddenAEDs are now widely available in public places
death or sudden cardiac arrest (SCA) or suddenwhere crowds tend to gather.
cardiac death.(3) Implantable Cardioverter Defibrillators (ICDs)
Cardiac arrest is not a heart attack. It is aare implanted in patients who have a high risk for
widespread misconception that SCA iscardiac arrest from recurrent, sustained
synonymous to a heart attack. In order toventricular tachycardia or fibrillation. An ICD
educate the public, the AHA and the Suddenautomatically reacts to irregular rhythms of the
Cardiac Arrest Coalition (SCAC) are quick to pointheart and applies an electrical jolt to restore
out the difference. A heart attack or myocardialnormal heart rhythms. According to the SCAC,
infarction occurs when the arterial supply orICDs are 98% effective at protecting those at
coronary arteries are compromised or blocked,risk for SCA, but only 35 percent of patients who
thus cutting off the blood supply to the heart.require this device have one. According to a New
And if allowed to continue will eventually lead toYork Times article "in the last two years the
infarction or injury to the heart muscles. "Thenumber of patients receiving defibrillators has
term "massive heart attack" is often wronglyactually declined, as more doctors and patients
used in the media to describe sudden death." Thedecide the risks and uncertainties the devices
SCAC has a beautiful analogy to explain to thepose may outweigh their potential benefits." More
general public: "If you think of your heart as arecently, the European Society of Cardiology
house - SCA would be a problem with the(ESC) issued a statement on driving restrictions
electricity; a heart attack would be a problem withfor patients implanted with ICDs.
the plumbing."(4) Cardiopulmonary resuscitation (CPR) works by
Cardiac arrest is not heart failure. In cardiac arrestattempting to maintain the blood flow to the
the electrical failure of the heart is sudden andheart and the brain until more effective
unexpected, whereas heart failure is progressivedefibrillation can be performed. About 80% of
but slow, thus allowing time for heart failureSCA cases happen at home, just like in the case
patients to eventually be considered as possibleof Michael Jackson. Therefore, CPR needs to be
heart transplant candidates.performed by bystanders, family members, and
Some people are more at risk for SCA thanpeople, even without medical training.
others.Unfortunately, only a third of out-of-hospital SCA
(1) SCA deaths are more common amongvictims receive bystander CPR and many die
women aged 35 to 44 years old compared tobefore the arrival of emergency services.
men of the same age. Women have also a lessImmediate effective bystander CPR can double or
chance of recovering from SCA than men.even triple a victim's dismal survival chances. A
(2) African Americans have a much higher risk to2008 survey by the AHA revealed that 80% of
suffer from SCA-related events than whites andrespondents said they were willing and able to do
other ethnic groups. They also have less than asomething to help if they witnessed a medical
1% chance of surviving, much lower compared toemergency. However, only a few (12%-20%) are
the 5% survival chance in the general population.confident that they would know when it is
(3) Some underlying conditions especially heartappropriate to perform CPR or use an AED.
problems make people more susceptible to SCASo, what could have caused Michael Jackson's
than others. Yet, even healthy individuals withoutcardiac arrest? Some of the possible causes
any health problems may suffer from SCA.based on Jackson's personal and medical history
There many things that can cause the heart to(Source: heartwire) include:
stop abruptly. Most of the cardiac arrests that(1) Overdose of prescription medications.
lead to sudden death occur when the electricalExpectedly this is the most popular theory but
impulses in the diseased heart become rapidwithout a toxicology report, this remains
(ventricular tachycardia) or chaotic (ventricularspeculative. It seems that Jackson was on
fibrillation) or both. This irregular heart rhythmprescription painkillers and two that may possibly
(arrhythmia) causes the heart to suddenly stopbe implicated in his death are Demerol
beating. Some cardiac arrests are due to extreme(meperidine) and Oxycontin (oxycodone). Dr
slowing (bradycardia) of the heart.Douglas Zipes of Indiana University Medical School,
So what causes the electrical system of theIndianapolis tells heartwire: "It's really where I
heart to fail?would go, but it's all very speculative at this point.
(1) Cardiovascular disease. According to the AHA,We know that depending on the type of
in 90% of adult victims of sudden cardiac death,painkillers, they can depress respiration. The initial
two or more major coronary arteries arestories are that he gradually slowed his
narrowed by fatty buildups. Scarring from a priorrespiratory rate and stopped breathing. That can
heart attack is found in two-thirds of victims.create hypoxia, which can produce ventricular
(2) Electric shock/electrocution. A strong electricfibrillation." The use of Diprivan for his insomnia has
shock, e.g. electrocution and lighting strikes canalso been implicated. Without an official toxicology
cause the heart to stop. Conversely, it also takesreport, all these however, remain as speculations.
an electric shock to restart the heart.(2) Complications from lupus. It is not a
(3) Respiratory arrest. When people cannotwell-known fact, but Jackson seemed to have
breathe during to choking, suffocation, drowning,been suffering from lupus, an inflammatory
or injury, SCA can also occur.disease that can also affect the heart and lead to
(4) Strenuous physical activity. There are casesa heart block.
of athletes suddenly collapsing during training or(3) Other heart diseases. A heart attack has also
competitions. This may be caused by underlyingbeen speculated but the singer did not have a
heart abnormalities. Adrenaline released duringhistory of heart disease and no other heart
intense physical activity acts as a triggeringconditions were detected during the most recent
mechanism for arrhythmia and sudden death.routine physical exam.
(5) Medications. Certain drugs, prescription or illegal,(4) Stress. It cannot be denied that Jackson was
can interfere with heart rhythms. When taken inunder too much stress. He was having major
excessive amounts, certain medications canfinancial problems and he was busy preparing for
completely stop the heart. Some of these drugsan international concert tour about to start in two
are: performance-enhancing drugs used in sports,weeks.
prescription drugs for heart problems, pain, andIt is without doubt that SCA is a major and
sleeping disorders especially insomnia, and illegal ordeadly health concern. Advocacy groups including
"recreation" drugs.the American Heart Association and the Sudden
(6) Trauma. A strong sudden blow to the heartCardiac Arrest Coalition are actively involved in
during sports competition for example, can causebringing this issue to the forefront. There are
a condition called Commotio cordis that can triggereven those who advocate the routine placement
ventricular fibrillation and lead to SCA. An injuryof AEDs in the homes of patients who are at high
that damages the heart can also lead to cardiacrisk.
arrest.